| C2_SIG_CHEMOTAXIS |
Genes related to chemotaxis |
| C2_SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES |
Genes related to regulation of the actin cytoskeleton |
| C3_WIZ_TARGET_GENES |
Genes containing one or more binding sites for UniProt:O95785 (WIZ) in their promoter regions (TSS -1000,+100 bp) as identified by GTRD version 20.06 ChIP-seq harmonization. |
| GOBP_AMYLOID_BETA_CLEARANCE |
The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors. [GOC:aruk, GOC:bc, GOC:BHF, PMID:18289866, PMID:19098903, PMID:26005850] |
| GOBP_BLEB_ASSEMBLY |
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] |
| GOBP_CORTICAL_ACTIN_CYTOSKELETON_ORGANIZATION |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. [GOC:dph, GOC:jl, GOC:mah, GOC:pf] |
| GOBP_EPITHELIAL_CELL_MORPHOGENESIS |
The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. [GOC:ascb_2009, GOC:dph, GOC:tb] |
| GOBP_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS |
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). [GOC:jl, http://www.copewithcytokines.de/] |
| GOBP_MEMBRANE_TO_MEMBRANE_DOCKING |
The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere. [GOC:isa_complete] |
| GOBP_MYOBLAST_MIGRATION |
The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:ai, GOC:mtg_muscle] |
| GOBP_NEGATIVE_REGULATION_OF_AMYLOID_PRECURSOR_PROTEIN_CATABOLIC_PROCESS |
Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process. [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:24499793] |
| GOBP_NEGATIVE_REGULATION_OF_DEPHOSPHORYLATION |
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf] |
| GOBP_NEURON_PROJECTION_ARBORIZATION |
The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites. [GOC:aruk, GOC:bc, PMID:17114044, PMID:23270857, PMID:23764288] |
| GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION |
Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization. [GOC:aruk] |
| GOBP_POSITIVE_REGULATION_OF_MUSCLE_HYPERTROPHY |
Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. [GOC:mtg_muscle] |
| GOBP_POSITIVE_REGULATION_OF_TISSUE_REMODELING |
Any process that activates or increases the frequency, rate, or extent of tissue remodeling. [GOC:add] |
| GOBP_REGULATION_OF_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY |
Any process that modulates the frequency, rate or extent of tight junction assembly. [GOC:BHF] |
| GOBP_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION |
Any process that modulates the frequency, rate or extent of endothelial cell differentiation. [GOC:go_curators] |
| GOBP_REGULATION_OF_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY |
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. [GOC:mah] |
| GOBP_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION |
Any process that modulates the frequency, rate or extent of keratinocyte differentiation. [GOC:go_curators] |
| GOBP_REGULATION_OF_SYNAPTIC_VESICLE_RECYCLING |
Any process that modulates the frequency, rate or extent of synaptic vesicle recycling. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22745285] |
| GOBP_RESPONSE_TO_ANGIOTENSIN |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen. [PMID:22982863] |
| GOMF_ASPARTIC_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY |
Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process. [GOC:ai] |
| GOMF_TAU_PROTEIN_BINDING |
Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS. [GOC:jid] |
| GOCC_BLEB |
A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] |
